Alessandro Mastrofini59 stories to explore, from the most recent.
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During my PhD, I had the opportunity to spend several months abroad. I chose to move to Rotterdam, a dynamic and international city known for its modern architecture, vibrant cultural scene, and strong focus on innovation. Home to…
Read more : Moving to Rotterdam
In silico medicine is built step by step, from medical images to computational models, each stage reveals a clearer picture of how the human body works. A small example developed in Wolfram Mathematica shows how clinical images of…
Read more : In-silico medicine and tendon biomechanics
Our new paper is out in the Journal of the Royal Society Interface ! In this study, we explore how homeostasis-driven vascular growth and remodelling modulate stress distributions in atherosclerotic carotid arteries. We extended…
Read more : Extending the cohort and improving the G&R
With the end of summer, an intense season of congresses has come to a close, months filled with inspiring discussions, new collaborations, and travels across Europe. It’s been both energizing and rewarding to share our research and…
Read more : Congresses closed the summerIn today’s classrooms, we’re witnessing a shift, not just in what we teach, but in how we teach. As the boundaries between disciplines blur and digital technologies become more immersive, traditional lectures are evolving into…
Read more : Feed the model, where theory comes alive
Thrilled to have participated in the ESB-ITA congress, where I had the chance to engage with top experts and innovators in the field of biomechanics. The Italian Chapter of the European Society of Biomechanics (ESB) brings together…
Read more : ESB-ITA in Pescara
The 29th Congress of the European Society of Biomechanics (ESB 2024) took place from June 30 to July 3, 2024, in the historic and vibrant city of Edinburgh, Scotland. This annual event gathers leading researchers, clinicians, and…
Read more : Exploring innovations in biomechanics: ESB 2024 congress in Edinburgh
As I pack my bags for the ECCOMAS 2024 congress in Lisbon, my excitement is twofold. Not only will I be immersing myself in the latest advancements in computational methods in applied sciences, but I’ll also be exploring one of…
Read more : Mechanics, models, and cobblestones: Lisbon ECCOMAS 2024
From the work of my Master's Thesis, I've taken a first step in the world of scientific publishing with the publication of my first paper: "On the Impact of Residual Strains in the Stress Analysis of Patient-Specific…
Read more : I published my first scientific paper
I recetly had the opportunity to host a course on Blender explaining its potentiality and usage to deal with biomechanical data such as medical scans, finite element analysis results, or general volumetric datasets. Blender Blender…
Read more : Scientific animation with Blender
I have been selected as one of the three best Master's Thesis in biomechanics competing for the ESB-ITA Master Thesis Award 2023. The Italian Chapter of the European Society of Biomechanics (ESB) brings together Italian ESB members…
Read more : I have been selected for the ESB-ITA Master Thesis Award
Computer graphics plays an important role in biomedical engineering by providing a visual representation of problems and solutions. It helps in many ways by providing a graphics instrument to share information with other fields…
Read more : 3D computer graphics in biomedical engineering
This journey started several years ago when I decided to enjoy the Medical Engineering course at the University of Rome Tor Vegata. More concretely, it started several months ago, moving to Stockholm and starting my traineeship at…
Read more : Diary of a thesis abroad - Final
This is my diary about my period abroad to develop my master’s thesis work on Vascular Biomechanics at the KTH Solid Mechanics department. I will tell the whole period in several articles, let’s continue with December. You can also…
Read more : Diary of a thesis abroad – Part IV
I started working as Bioengineering Application Developer for Mathematica in the Wolfram company. Several weeks ago I was contacted by the Numerical Computation group of Wolfram offering me a fixsed term internship to work on…
Read more : Bioengineering Application Developer at Wolfram
This is my diary about my period abroad to develop my master’s thesis work on Vascular Biomechanics at the KTH Solid Mechanics department. I will tell the whole period in several articles, let’s continue with November. You can also…
Read more : Diary of a thesis abroad – Part III
This is my diary about my period abroad to develop my master’s thesis work on Vascular Biomechanics at the KTH Solid Mechanics department. I will tell the whole period in several articles, let’s continue with October. Week 4 It is…
Read more : Diary of a thesis abroad - Part II
During my stay in the KTH Solid Mechanics department I had the opportunity to visit the soft tissue mechanics laboratory and to try an uniaxial tensile test on tissue from a porcine aorta. I had the opportunity to participate in…
Read more : Visitor to the soft tissue mechanics lab
This is my diary about my period abroad to develop my master's thesis work on Vascular Biomechanics at the KTH Solid Mechanics department. I will tell the whole period in several articles, let's start with September. I had the…
Read more : Diary of a thesis abroad - Part I
I finished my experience in the Summer School entitled "Computational Tissue Biomechanics: From in-vitro experiment to computational analysis". The course introduces and applies state-of-the-art tools in the continuum mechanical…
Read more : Biomechanics Summer School
I am starting an internship at the KTH Royal Institute of Technology in Stockholm, Sweden, for a master's thesis in biomechanics. KTH KTH (in swedish, Kungliga Tekniska högskolan ) know as Royal Institute of Technology is a public…
Read more : Trainee at KTH Royal Institute of Technology
The introduction of CFD in the design and re-design phases of hospital environments allows us to estimate air speed, temperature and track the spread of pollutants / pathogens. In particular, it is possible to use these tools to…
Read more : CFD analysis of ventilation inside an operating room
Cardiovascular diseases are the cause of numerous deaths. Among these, abdominal aortic aneurysms are very dangerous for which adequate techniques for diagnosis and prevention have not yet been developed. The implementation of…
Read more : Aneurysm and biomechanics of vessels
The characterization of the mechanical properties of the cell is of great importance for estimating its biological state and physiology. Among the different measurement techniques, through the microrheometer it is possible to…
Read more : Microrheometer and viscoelastic properties of cells
The equivalent circuit model for a parallel electrode impedance cytometer is analyzed together with Maxwell's theory of homogenization of mixtures. It deals with both single shell and double shell cell modeling. The results show…
Read more : Impedance cytometer and circuit equivalent
Mathematical modeling of diffusion mechanisms for drug delivery can be very useful for accelerating product development and for better understanding the mechanisms that control drug delivery from advanced delivery systems. The…
Read more : Diffusion and FEA for drug-eluting spheres
Glucose is essential for human life and its concentration in the blood is strictly regulated. Alterations in blood glucose are a sign of numerous diseases and several clinical tests are used for diagnosis. The IVGTT test is a…
Read more : Glucose minimal model and IVGTT test
Physiological reflexes are the basis of the organism's survival. These reflexes allow, in a completely involuntary way, to maintain homeostasis. Variations in environmental variables or the appearance of a new signal induce a…
Read more : Physiological reflexes and control systems
Parametric optimization analysis on a hip prosthesis stem subject to two load scenarios aimed at minimizing its mass while maintaining the stress state below the design limits. The following article is an extract from a project…
Read more : Parametric optimization in prosthetic design
In impedance cytometry, various design and post processing techniques have been developed to improve measurement accuracy. One of the parameters that most afflicts cytometry measurements is the dependence of the signal on the…
Read more : Curve fitting and compensation for impedance cytometry signals
FEM analysis aimed at characterizing the mechanical behavior of the stem of a hip prosthesis inserted inside a femur. The following article is an extract from a project carried out for the course of Advanced Techniques for the…
Read more : Mechanical simulation of hip implant
A linear model of lung mechanics is analyzed in the following report. The model corresponds to an RLC circuit with unknown parameters. Parametric identification allows to trace the system governance coefficients once a mathematical…
Read more : Parametric identification for respiratory mechanics
Pulmonary ventilation is a critical operation both during surgery and for assisted or replacement ventilation of the patient. This report proposes the analysis of a lung mechanics model through an electrical analogy with an…
Read more : Lung ventilation in Simulink
In the digital era, even in medicine, numerous images are produced every day and, despite their classification, the segmentation and recognition of objects are less detailed. With the recent development of artificial intelligence…
Read more : Deep learning and segmentation in cell biology
In this period I had the opportunity to gain different experiences in the design and construction of antennas. In particular, the latest experiences have focused on the study and design of patch antennas and antenna arrays.…
Read more : Folded patch antenna prototyping
In most phenomena it is often necessary to take into account, in addition to the mechanical characteristics, various other quantities. For example, it is important to analyze the variation over time of quantities such as…
Read more : Multiphysics computational models and poroelasticity
In this analysis some computational models are introduced for the finite element analysis of isotropic and kinematic hardening behaviors. The response to a cyclic load is analyzed for some stainless steels. These simulations…
Read more : Elasto-plastic numerical models
The latest developments in Computer Aided Engineering, by means of the remarkable progress that several softwares have been made in terms of computational speed and of enlarged ranges of phaenomena that can be simulated and…
Read more : Development and Analysis of an Array of Folded Patch Antennas Using Matlab
In the present analysis several simulation analysis were carried out to analyze the structural response of CF / PEEK laminated composites showing great potential for application in the biomedical field. Background , in a laminated…
Read more : Laminated composites and structural elements
Automated computational modeling (ACM) is a fairly recent technique that exploits a hybrid approach by combining symbolic computation with numerical computation. These potentialities can be exploited in finite element formulations…
Read more : Automated Computational Modeling
This image processing algorithm arises from the need to have a 3D volume starting from the slices of a CT. There are several algorithms online but most require DICOM images. In this case, the reference dataset is made up of 970 png…
Read more : Volumetric image processing over trabecular bone
The following report introduces various simulation campaigns aimed at homogenizing trabecular bone tissue. Background , analyzing the structure of the trabecular bone it is evident how the shape of the pores and the trabecular…
Read more : Numerical homogenization of trabecular bone
Modern computers have all the prerequisites for developing numerical resolution methods for a large class of physical problems that have been left without an analytical solution for years. There are several numerical solution…
Read more : MoM and electric intregrodifferential equations
Among the exams scheduled in the Medical Engineering course at the University of Rome Tor Vergata there is the course of Wireless Electromagnetics Technologies. The course provides the foundation for current and next generation…
Read more : Design with Sensor Array Analyzer
In resistance training there are three exercises that are considered "fundamental" and have become the emblem of weightlifting: squat, bench press and deadlift. Focusing more on the aspect of strength training , therefore of…
Read more : Growth model for foundamentals lifts
Esplora gli ultimi sviluppi informatici e tecnologici, enfatizzando programmazione, elettronica, robotica, automazione intelligenza artificiale. Il network di Close Up Engineering è un punto di riferimento italiano, e non solo, per…
Read more : Articoli per la sezione Tech CuE
Leggi di più sull'articolo scritto per CuE dove parlo del robot realizzato con una piattaforma Stewart con cui viene simulato il movimento cardiaco. Tramite 6 gradi di libertà consente di inseguire traiettorie e assetti rilevati da…
Read more : Robot esapode per simulare il movimento cardiaco
Un nuovo articolo scritto per BiomedCuE alla luce di una recente pubblicazione sulla risposta immunologica al Covid19 durante la gravidanza. Alcuni spunti di riflessione sulla situazione attuale per le donne in gravidanza durante…
Read more : Covid19, medicina di genere e gravidanza
Dove l’ingegneria incontra la passione per la medicina, lì nasce l’ingegneria biomedica: la tecnologia applicata all’essere umano. Il network di Close Up Engineering è un punto di riferimento italiano, e non solo, per…
Read more : Articoli per la sezione Biomed CuEI finished the course "The Data Science of Healthcare, Medicine, and Public Health, with Barton Poulson" taught by Barton Poulson. The course addresses from a non-technical point of view different sectors in which it is possible to…
Read more : Data Science of Healthcare, Medicine, and Public Health
GitHub repository Download report (it) --- The aim of the project is to show how it is possible to control a clamp and its rotation through a signal from some sensors such as an inertial sensor and an electromyography sensor. The…
Read more : Robotic clamp controlled by gyro and electromyography
GitHub repository --- The project involves the creation of one or more monitoring stations of the domestic environment which can possibly, with due care, be extended to public and / or corporate environments. --- On this page ---…
Read more : Environmental comfort monitoring unit
Una nuova tecnologia per il biosensore per SARS-CoV2 realizzato su un transistor ad effetto di campo al grafene. Il biosensore COVID-FET è sensibile alla proteina spike ed ha mostrato un'elevata sensibilità. Per approfondirne il…
Read more : COVID19 - FET: biosensore con transistor ad effetto di campo al grafene
Leggi il mio ultimo articolo sull'intervento innovativo svoltosi a Parma al Piccole Figlie Hospital dove è stata realizzata una chirurgia protesica alla spalla sfruttando la realtà aumentata. Vai all'articolo completo Scopri di più…
Read more : Piattaforma NextAR e chirurgia protesica con realtà aumentata
Approfondisci il funzionamento e la storia del misuratore di glicemia, uno dei biosensori più diffusi al mondo, con l'articolo che ho scritto per il portale di Close - Up Engineering. Come funziona, come utilizzarlo e quali…
Read more : Come funziona il glucometro ?
Beginning of a path as editor for the BioTech Macroarea: BiomedCuE - ScienceCuE - TechCuE. Editor, web-optimized writing, social editorial management. --- CuE is the network of sites dedicated to scientific dissemination with…
Read more : Editor for Close-Up Engineering
See the full repository Design of a prototype for a rehabilitation system for the ankle joint based on US patent 6,277,057B1. Bioprothesis course University of Rome Tor Vergata
Read more : Ankle rehabilitation deviceThe concept of " customization " has become quite common nowadays, especially when it comes to the technological field: a certain object becomes of interest to us when it satisfies our specific needs, whatever they may be. The…
Read more : Patient specific diagnostics for cardiovascular diseases
The test allowed me to investigate and experience in practice how the ear responds and perceives different frequencies differently using the MATLAB software and home earphones, without resorting to professional equipment. After an…
Read more : Construction of the Fletcher-Munson curve